Paget's Disease of Bone (also known as Osteitis Deformans) is a chronic condition that disrupts the normal cycle of bone remodeling, where the bone tissue is broken down and replaced. In Paget's disease, this process goes awry, leading to the formation of abnormally large, weak, and disorganized bones. This can result in pain, deformities, and fractures. The disease most commonly affects the pelvis, spine, skull, and legs. Common Signs & Symptoms of Paget's Disease: Bone Pain: Often the first sy