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  1. Scleroderma - Symptoms and causes - Mayo Clinic

    Jun 15, 2024 · Early symptoms may include swelling and itchiness. The color of affected skin can become lighter or darker, and skin may look shiny because of the tightness. Some people also …

  2. Scleroderma: Symptoms, Causes & Treatment Options

    What is scleroderma? Scleroderma is a rare condition that makes your body produce tissue that’s thicker than it should be. Scleroderma usually affects your skin, but can cause symptoms in …

  3. Scleroderma: Signs and symptoms - American Academy of …

    Some people develop 1 or 2 patches of hard, thick skin. Others have widespread patches on their body. The hard, thick skin can feel anchored in place. If you have morphea (more-fee-uh), the …

  4. Scleroderma Symptoms - Johns Hopkins Medicine

    The symptoms of scleroderma may vary and can look quite different in each person. In some people, it only affects the skin, but in others, scleroderma goes much deeper, harming your …

  5. Scleroderma Symptoms, Types, Causes, & Risk Factors | NIAMS

    The fibroblasts live longer than normal, causing a buildup of collagen in the skin and other organs, leading to some of the signs and symptoms of scleroderma. There can also be injuries to …

  6. Systemic Sclerosis (Scleroderma): Pictures, Symptoms, Causes

    Sep 11, 2025 · With SS, your tissue becomes thick and stiff, leading to swelling and pain. It also causes changes to the texture and appearance of your skin due to increased collagen …

  7. Scleroderma Symptoms - WebMD

    Sep 3, 2024 · Scleroderma symptoms are different for each person. Your symptoms depend on the type of disease you have. The thing you’re most likely to notice first is that the skin on your …

  8. Scleroderma SymptomsScleroderma Education Project

    Scleroderma Symptoms This section includes a list of possible symptoms that can occur with different forms of systemic scleroderma.

  9. Scleroderma – Symptoms and Causes | Penn Medicine

    Scleroderma is a rare autoimmune disease that triggers your immune system to make too much collagen. This results in hardened, tight skin and connective tissue that can lead to muscle and …

  10. Variety of scleroderma symptoms | More Than Scleroderma

    Your scleroderma symptoms and how they may change in the future are unique to you. Learn about which organs and body parts can be affected by the SSc.