Compared to rat brains, humans express more CB 1 receptors in the cerebral cortex and amygdala and less in the cerebellum, which may help explain why motor function seems to be …

CB1 receptors are G-protein coupled receptors (GPCRs) abundant in neurons, in which they modulate neurotransmission. The CB1 receptor influence on memory and learning is well …

Jul 23, 2025 · CB1 receptors are specialized proteins found on the surface of cells throughout the human body. They function as receiving antennas, interacting with chemical signals that help …

The cannabinoid-1 receptor (CB1 receptor) is a pivotal component of the endocannabinoid system, extensively expressed in the central nervous system where it modulates …

In this review, we briefly summarized our knowledge of cannabinoids and the endocannabinoid system, focusing on the CB1R and the CNS, with emphasis on recent breakthroughs in the field.

Cannabinoid receptor type 1 (CB 1) receptors are thought to be one of the most widely expressed G αi protein-coupled receptors in the brain.

Sep 1, 2017 · In this section, we will discuss the heterogeneity of CB 1 receptor signaling in the CNS.

Jan 4, 2017 · In this review, we will provide a general overview of the ECS with emphasis on the CB 1 receptor in health and disease.

Jul 26, 2025 · Within the brain, CB1 receptors are abundant in areas such as the neocortex, hippocampus, basal ganglia, and cerebellum. Their presence in these regions explains their …

Feb 26, 2025 · CB1 receptors are a type of G protein-coupled receptor (GPCR) that is widely distributed throughout the central nervous system. They are triggered by cannabinoids, which …