Can Ohio State run enough? Will Georgia's D show up? What could trip up Indiana? We look at the best teams' weak spots.

The Big 12 takes the spotlight during the Week 11 college football schedule with a huge top-10 matchup between No. 7 BYU and No. 8 Texas Tech. BYU leads the Big 12 (5-0), with Texas Tech one game back, but it is the Red Raiders who are 11.5-point home favorites in the latest Week 11 college football odds.

The top four teams of last week's US LBM Coaches Poll and CFP top 25 — No. 1 Ohio State, No. 2 Indiana, No. 3 Texas A&M and No. 4 Alabama — won their Week 11 contests, setting up potential championship games between the Buckeyes and Hoosiers in the Big Ten and Aggies and Crimson Tide in the Southeastern Conference.

BYU can earn a rematch with Texas Tech by winning its next three games. BYU faces the Cincinnati Bearcats, the other one-loss team in Big 12 play, on November 22 in Ohio. A BYU win over Texas Tech in the Big 12 Championship Game feels like the only path for the conference to get two teams into the 12-team field now.

Joe Fagnano has been nails for UConn this season. The Huskies improved to 7-3 with their Week 11 upset of Duke -- handing coach Jim Mora his third win against the ACC since the start of the 2024 campaign -- and are on track to have one of their best seasons since the turn of the century behind the arm of Fagnano.

Oklahoma is off in Week 11 of the season after its impressive 33-27 road win over Tennessee on Nov. 1. It's the Sooners' second and final off week of the season. Oklahoma was also off Sept. 27, ahead of games against Kent State and Texas.