TFE3 fusion proteins are the oncogenic drivers of translocation renal cell carcinoma but their mechanism of action remains ...

Researchers have used genetic tools to investigate how specific nerve cells in the brain respond after a spinal cord injury.

A new study reveals that metformin, beyond managing blood sugar, restores endometrial health in women with PCOS. The drug ...

Researchers have detailed the precise mechanism through which the inflammatory signaling molecule IL-12 contributes to Alzheimer's disease.

A new study reveals that IL-12, an inflammatory molecule, accelerates Alzheimer’s disease by damaging brain cells and ...

Microglia, the brain's immune cells, usually serve as diligent guardians. They eliminate intruders such as microbes and clear ...

He reasoned that single cell analyses might provide more decisive ... Instead of isolating entire cells, they extract cell nuclei from brain tissue and analyze the RNA present in each cell. By ...

In Nature Neuroscience, UConn School of Medicine researchers have revealed a new scientific clue that could unlock the key ...

We can accept submissions of 10x Genomics single-cell or single-nuclei profiling of childhood and adolescent ... We’re seeking collaborators with experience analyzing single-cell RNA-seq datasets to ...

Methods Single-nucleus RNA sequencing of 82 924 nuclei from 21 IFPs (n=6 healthy control and n=15 KOA donors), spatial transcriptomics and bioinformatic analyses were used to identify contributions of ...

SEATTLE--(BUSINESS WIRE)--Parse Biosciences, the leader in accessible and scalable single cell sequencing, today affirmed their plans to proceed with development and future release of their ...