Single-cell sequencing applications have accelerated breakthroughs in life sciences, leading to significant impacts for disease treatments. Single-nuclei RNA-sequencing (snRNA-Seq) has been shown to ...

This important study offers a molecular characterization of neurons and glia in the adult nervous system of the fruit fly Drosophila melanogaster. The study focuses on the progeny of a specific set of ...

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as ...

This difficulty has consequently made it more difficult to isolate intact nuclei or protoplasts, which are necessary for a thorough examination. Now, single-cell RNA (scRNA) sequencing has made ...

Study design, alignment, SNPs, indels, CNVs, structural variants, annotation, visualization, network analysis, variant interpretation and classification ...

The team used two forms of single-nucleus RNA sequencing (snRNAseq ... Using snRNAseq avoids that dilemma by isolating the nuclei of each cell in a sample. Then, scientists can analyze the ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...