Single-cell sequencing applications have accelerated breakthroughs in life sciences, leading to significant impacts for disease treatments. Single-nuclei RNA-sequencing (snRNA-Seq) has been shown to ...

Spatial transcriptomics is a cutting-edge technique that characterizes gene expression within sections of tissue, such as ...

The team used two forms of single-nucleus RNA sequencing (snRNAseq ... Using snRNAseq avoids that dilemma by isolating the nuclei of each cell in a sample. Then, scientists can analyze the ...

This important study offers a molecular characterization of neurons and glia in the adult nervous system of the fruit fly Drosophila melanogaster. The study focuses on the progeny of a specific set of ...

This difficulty has consequently made it more difficult to isolate intact nuclei or protoplasts, which are necessary for a thorough examination. Now, single-cell RNA (scRNA) sequencing has made ...

Using single-cell RNA sequencing, we mapped thousands of expression quantitative trait loci in yeast, including a variant in GPA1 that influences gene expression, cell-cycle occupancy, and mating ...

Study design, alignment, SNPs, indels, CNVs, structural variants, annotation, visualization, network analysis, variant interpretation and classification ...