Background Effective management of coexisting heart failure (HF), chronic kidney disease (CKD) and type 2 diabetes mellitus (T2D) is critical, yet evidence of adherence to guideline-recommended ...

Following injury, many organs are capable of rapid regeneration of necrotic tissue to regain normal function. In contrast, the damaged heart typically replaces tissue with a collagen-rich scar, due to ...

For over two decades, a ‘treatment-risk paradox’ has been described in older adults with cardiovascular disease, with persistent undertreatment of high-risk older patients with effective ...

Background There is substantial interest in the cardiovascular effects of e-cigarette use, highlighting the need to update our knowledge on the subject. We conducted this review to analyse whether ...

Introduction UK and US Guidelines now recommend HeartFlow FFR-CT (Fractional Flow Reserve-Computed Tomography) in stable chest pain (CP), but its clinical effectiveness and costs in real-world ...

Background Pulmonary hypertension (PHT) lacks community prevalence and outcome data. Objective To characterise minimum ‘indicative’ prevalences and mortality data for all forms of PHT in a selected ...

Objective To assess the long-term functional and health-related quality-of-life (HRQoL) outcomes for out-of-hospital cardiac arrest (OHCA) survivors stratified by initial defibrillation provider.