The Duke Blue Devils are the favorite to bring home the national title at +175. The Florida Gators are the second choice to win the NCAA Tournament at +320 odds.Start the day smarter. Get all the news you need in your inbox each morning.

Fanatics also has daily odds boosts and arguably the best rewards program around. Bettors earn FanCash with every wager, which can be converted into bonus bets at the sportsbook and used on March Madness games. It can also be used as site credit at Fanatics’ retail website, where you can buy merchandise of your favorite teams and players.

Who is the favorite to win the 2025 NCAA Tournament entering the Sweet 16 games? Check out national title odds for every team left in March Madness.

The No. 2 seed Spartans (29-6) face the No. 6 seed Ole Miss Rebels (24-11) in Atlanta, Georgia. The winner will face either No. 5 seed Michigan (27-9) or No. 1 seed Auburn (30-5) Sunday in an Elite 8 game.

Mobile sportsbooks, including 11 licensed in Maryland, are permitted to limit the bets of big-spending customers it believes possess advantages such as statistical modeling.

SportsLine's Mike McClure, a daily Fantasy pro with more than $2 million in winnings, gives optimal NBA DFS lineup advice for Monday, March 24

The No. 5 seed Wolverines (27-9) face the No. 1 seed Auburn Tigers (30-5) in Atlanta, Georgia. The winner will take on either No. 2 seed Michigan State (29-6) face the No. 6 seed Ole Miss (24-11) Sunday in an Elite 8 game.

As the NCAA Tournament's East Regional returns to Newark for the first time since 2011, a look at the inner workings -- and what's next for the venue.