hMTH1 recognizes two oxidized dNTPs as shown in the 3-D structure (upper area of figure: hMTH1, ribbon; damaged dNTPs, sticks). The determining factor in the broad substrate specificity is differing ...
With the technique called polymerase chain reaction (PCR), scientists can make multiple copies of a specific genetic sequence within DNA. PCR is a powerful tool for researchers because it allows for ...