A new review highlights how synthetic biology, AI, and spatial omics could transform ligand-receptor discovery from one-by-one searches into network-level mapping.
Co-first author Jiyuan Yang, PhD, St. Jude Department of Computational Biology and co-senior and corresponding author Jiyang Yu, PhD, St. Jude Department of Computational Biology interim chair look at ...
Spatial transcriptomics is revolutionizing the study of tissue architecture, cellular states, and tumor-immune interactions in clinical specimens. This presentation introduces the principles and ...
A comprehensive review article titled “Bioinformatics perspectives on transcriptomics: A comprehensive review of bulk and single-cell RNA sequencing analyses,” published in Quantitative Biology, ...
Fei Chen and Chenlei Hu at the Broad Institute of MIT and Harvard have developed a new imaging-free spatial transcriptomics technology that tracks the diffusion of DNA barcodes between beads in an ...
Biological systems are inherently three-dimensional—tissues form intricate layers, networks, and architectures where cells interact in ways that extend far beyond a flat plane. To capture the true ...