This image illustrates the process of gene transcription within a cell. The DNA double helix unwinds to expose a specific sequence, allowing RNA polymerase to synthesize a complementary pre-mRNA ...
As animals and people age, there are changes in the genome. Telomeres, the protective ends of chromosomes, get shorter as cells continue to divide; some cells will pick up mutations in their genomes ...
AI maps fleeting DNA quadruplexes, revealing paired structures that control genes in healthy cells and cancer.
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Hidden DNA weak spot near gene start mutates rapidly

These sequences are extremely prone to mutations and rank among the most functionally important regions in the entire human ...
XPC protein acts as a sensor to detect various abnormalities in the DNA structure. The faithful repair of DNA is ensured by using the basal transcription factor TFIIH and XPA protein to verify the ...
An international team, including researchers from HSE University, has created the first comprehensive map of ...
A particularly slippery transcription factor, MYCN, is thought to stimulate tumor cell growth and proliferation through amplification of gene transcription. MYCN and like proteins are slippery in the ...
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The Shape of Your DNA Matters

Researchers created the most detailed maps yet of the genome’s three-dimensional organization using human stem cells and ...
Baylor College of Medicine researchers report that they found the mechanism by which normal brain cells regulate the expression of the NFIA, or nuclear factor IA, gene, which is critical for both ...