Mutant gene behind aggressive adult leukemia offers new clues for treatment

Imagine a tiny superhero inside every cell of your body whose job is to stop damaged cells before they turn dangerous. That ...

Targeting the untargetable cancer—rezatapopt, an oral p53 reactivator

Memorial Sloan Kettering Cancer Center investigators and collaborators have tested rezatapopt, an oral p53 reactivator ...
Medindia

Cat Cancer Genes Show Striking Similarities to Human Tumors

Large genomic study of feline tumors identifies shared mutations with human cancers, strengthening comparative oncology ...

What is a 'cancer gene'? How genetic mutations lead to cancer

An estimated 170,000 Australians were diagnosed with cancer in 2025. Many people know the causes of cancer are partly genetic. But how do your genes, which contribute so much of what makes you you, ...
ascopubs.org

Effect of co-occurring TP53 and intracellular proliferation pathway mutations on disease recurrence and survival benefits in head and neck cancers.

Dysphagia in cancers of the lip, oral cavity, and pharynx patients: Impact on cachexia, hospitalization, and racial disparities on outcomes. This is an ASCO Meeting Abstract from the 2025 ASCO Annual ...
ascopubs.org

TP53 mutation as predictive factor of platinum response in BRCA-mutated ovarian cancer: A prospective case-series analysis.

Exploration of the application of the sprayed γ-GGT fluorescent probe for visual imaging of epithelial ovarian cancer. This is an ASCO Meeting Abstract from the ASCO Breakthrough: A Global Summit for ...