Drug discovery is like molecular Tetris. Chemists snap atoms together, adjusting the pieces until everything fits, and ...

Mechanochemical synthesis harnesses mechanical energy to drive chemical transformations under solvent‐minimised or solvent-free conditions. This approach, frequently executed by ball milling or liquid ...

A team at ETH Zurich developed a new peptide-based organocatalyst that handles macrocycle formation from start to finish.

Researchers develop a one pot process to transform aromatic ketones to esters, offering advancements in pharmaceutical synthesis and materials science. Aromatic ketones have traditionally been ...

Researchers at Nagoya University have created a more efficient iron-based photocatalyst that could reduce the need for rare and expensive metals in advanced chemistry. Unlike earlier designs, the new ...

Karthik Sankaranarayanan trained in two quite different scientific subfields as a graduate student and as a postdoctoral ...

As an engineering plastic having high transparency and impact resistance, polycarbonate (PC) is employed in eyeglass lenses, camera lenses, DVDs, automobile headlights and bulletproof glass. The ...

Fortunately, these giant rings are about to become a lot easier to access. Helma Wennemers and her team at ETH Zurich have ...

With artificial intelligence, scientists can design increasingly complex small molecule structures. Automation is critical for transforming these compounds from designs on a screen into actual ...

Advancements in peptide and oligonucleotide synthesis via precision chemistry are transforming therapeutic development by ...

A blue-light-powered iron catalyst just replaced rare metals — and unlocked a milestone in precision drug synthesis.