To determine whether bacterial ribosomes recognize a distinguishing feature in the immediate vicinity of actual initiator codons or are directed to these sites through involvement of other portion(s) ...

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a beta-CoV that recently emerged as a human pathogen and is the causative agent of the COVID-19 pandemic. A molecular framework of how ...

This image highlights two alternatives for the ribosome to be recruited to an mRNA that is still being synthesized by RNA polymerase (RNAP). RNAP (left, red) can directly deliver the mRNA to the entry ...

Protein biosynthesis in cells begins with translation initiation, an extraordinarily complex process in which a ribosome assembly binds to an mRNA gene transcript, recognizes its start codon, and ...

Having solved the first crystal structure of a eukaryotic ribosome, scientists are now getting a new, more detailed look at the machinery that translates the genetic code into proteins in all living ...

A group of scientists has succeeded in the development of modified messenger RNAs (mRNAs) that contain sulfur atoms in the place of oxygen atoms of phosphate moieties of natural mRNAs. They discovered ...

It is unlikely that Shakespeare was thinking of ribosomes when he warned against hastiness. But it turns out, for ribosomes too, “wisely and slow” does not really cut it as they go about their ...

DNA translation is the term used to describe the process of protein synthesis by ribosomes in the cytoplasm or endoplasmic reticulum. The genetic information in DNA is used as a basis to create ...