The bacterial Rho factor is a ring-shaped ATP-dependent helicase that tracks along RNA transcripts and disrupts RNA-DNA duplexes and transcription complexes in its path. Using combinatorial nucleotide ...

(New York, NY, January 13, 2009) A new study led by researchers at NYU Langone Medical Center is shedding new light on the action of Rho, a key regulatory protein in E. coli and many other bacteria.

Transcription termination in Escherichia coli is a finely tuned process that ensures precise regulation of gene expression. It involves both intrinsic and factor-dependent mechanisms. Intrinsic ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 105, No. 47 (Nov. 25, 2008), pp. 18159-18164 (6 pages) In fast-growing bacteria, ribosomal RNA (rRNA) is required ...

DNA replication fork movement is impeded by collisions with transcription elongation complexes (TEC). We propose that a critical function of transcription termination factors is to prevent TEC from ...

KAIST announced on the 27th that a joint research team, led by Professor Emeritus Changwon Kang of the Department of Biological Sciences and Professor Seong-Cheol Hong of the Department of Physics and ...

A new study is shedding new light on the action of Rho, a key regulatory protein in E. coli and many other bacteria. The study reveals a new paradigm to understand the molecular principles of gene ...