In previous clinical trials involving children with X-linked severe combined immunodeficiency (SCID-X1), a Moloney murine leukemia virus–based γ-retrovirus vector expressing interleukin-2 receptor ...

As a lab within the Cooperative Center of Excellence in Hematology (CCEH) at Fred Hutch, the Vector Production core assists investigators with the design, construction, and/or production of viral ...

Doctors at UCLA, Cleveland Clinic, University of California San Diego School of Medicine and additional institutions have achieved a milestone in the development of a treatment for people with ...

We transferred new genetic information into human cell lines and hematopoietic stem cells using retrovirus vectors. These vectors, containing the dominant selectable gene (neo) for resistance to the ...

Retroviral vectors that are both non-replicating and non-integrating represent a novel and attractive tool that has potential advantages for gene delivery therapy, immunotherapy, and vaccinology. SAN ...

Treatment of unresectable thymoma with neoadjuvant octreotide LAR. Background: Patients with the most common and aggressive form of brain cancer, glioblastoma multiforme (GBM) have poor prognosis and ...