The Philadelphia 76ers took a key loss to the Toronto Raptors on Wednesday 118-105 as they have lost two in a row and five of their last six games. The loss to the Raptors was especially key as Toronto has now won the first three matchups with Philadelphia and the Sixers own the "tiebreaker" in the reverse standings.

Quentin Grimes was again the Sixers’ primary offensive threat, finishing with 29 points, four rebounds, and three assists.

Here are the three biggest takeaways for the Philadelphia 76ers following their latest loss to the Toronto Raptors on Wednesday.

We've got another exciting Atlantic Division matchup on Wednesday's NBA schedule as the Philadelphia 76ers will visit the Toronto Raptors. Toronto is 22-43 overall and 15-20 at home, while Philadelphia is 22-42 overall and 10-21 on the road.

The 76ers are currently 10-21 on the road with a point differential of -5, while the Raptors have a 4-6 record in their last ten games at home. Toronto won both meetings by three