Every cell depends on proteins to function and stay healthy. These proteins are made inside the cell from amino acids but cannot simply accumulate inside the cell forever. Once they have done their ...

A new study led by Pierre Close's team (GIGA, Laboratory of Cancer Signaling, and WELRI Investigator) reveals how subtly ...

Imagine a breakthrough in cancer treatment where only malignant cells are targeted, sparing healthy host cells; or patients with abnormal protein synthesis are treated to produce a healthy protein.

Janelia researchers have uncovered a novel way that two of the structures inside cells—the endoplasmic reticulum (ER) and lysosomes—coordinate the production of proteins, highlighting how interactions ...

A team of researchers has uncovered a previously unrecognized role of mitochondrial protein synthesis in the maintenance of intracellular iron distribution. Disruption of this process was found to ...

Research identifies ribosome biogenesis factor MYBBP1A as a driver of acute myeloid leukaemia growth, highlighting a ...

Chemists from ETH Zurich have found a way to produce poorly soluble proteins by caging a uniquely reactive boron compound. This method opens up new possibilities for the synthesis of tailored protein ...

Many biological functions are regulated by the switching on and off of mechanisms triggered by the matching of a keyhole (receptor) formed by a protein's three-dimensional structure and a molecule ...

As we age, the composition and function of proteins in the brain change, affecting how well our brain performs later in life—influencing memory, responsiveness, and the risk of neurodegenerative ...

Imagine a cancer treatment that precisely targets malignant cells, leaving healthy ones untouched. Consider, also, a cancer treatment that corrects abnormal protein synthesis to produce healthy ...