The reliable nature of the DNA base pairing rules discovered by Franklin, Watson, and Crick 1,2 is crucial to maintaining accurate replication of genetic material. A low but finite rate of DNA ...

In real life, mutants can arise when their DNA changes to give them an advantage over the rest of the population. A team from the University of Michigan has used simulations on the Pittsburgh ...

Example of a spatial configuration of a 2D expanding and evolving colony of cells, a typical simulation representing an example with 3 mutations. The individual graphs represent different snapshots in ...

The mutation rate of a specific position in the human genome depends on the sequence context surrounding it. Modeling the mutation rate by estimating a rate for each possible k-mer, however, only ...

Imagine a virus is like a key, and the cells it can infect are like locks. A virus can’t infect any cell of any animal; it needs to find a cell with the right “lock” (called a receptor) or change its ...