Given how profound an influence opioids have on the world – for better or worse – scientists know surprisingly little about how these drugs actually work. A recent study led by researchers from ...

Drugs that target opioid receptors sometimes have severe side effects. Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Researchers have taken a ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 119, No. 16 (April 19, 2022), pp. 1-10 (10 pages) Allosteric modulators of G-protein-coupled receptors (GPCRs) ...

Opioid agonist/antagonist has a big impact in phase IIb trial ...

Muse Treatment Alcohol & Drug Rehab Los Angeles has published a new educational resource that explains how opioid receptors function in the brain and why they play a central role in pain relief, ...

Epidermal growth factor receptor (EGFR) signaling in the tissue around oral cancers both increases nerve sensitivity and ...

Thousands of people around the world die every day from overdoses involving opioids such as fentanyl. Drugs that target opioid receptors sometimes have severe side effects. An international team of ...