Cells and their organelles are surrounded by lipid membranes that act as ‘gatekeepers’ by controlling the exchange of cellular components and materials. Most membrane lipids are synthesized in an ...

Edward Lyman, associate professor in the departments of physics and astronomy, as well as chemistry and biochemistry, was recently published in the journal Nature Chemical Biology. The article, “When ...

A new tool developed by Helmholtz Munich and the German Center for Diabetes Research and the University of Bonn makes spatial proteomics and lipidomics easier to use—no coding required. C-COMPASS ...

Membrane proteins and membrane lipids are essential partners in various biological processes, and elucidating their ...

Researchers in Bochum have discovered a control mechanism that may also operate beyond plants. Proteins carrying a "tail anchor" must be inserted into the ER membrane before they can fulfill their ...

The endoplasmic reticulum (ER) is the portion of the cell responsible for manufacturing and folding proteins. Proteins are essential for a wide range of cellular functions-as enzymes, transporters, ...

The human gut is home to trillions of microbes that not only aid in digestion but also play a key role in shaping our immune system. These microbes communicate with the body by releasing a range of ...

Lipids are difficult to detect with light microscopy. Using a new chemical labeling strategy, a Dresden-based team led by André Nadler at the Max Planck Institute of Molecular Cell Biology and ...

The result is adipocytes accommodating larger lipid droplets – and increasing the size of these fat cells. “This study nudges us a little closer to the clinic by revealing a brand-new handle on how ...

Aβ and tau get much of the glory in Alzheimer’s disease, but the disease is far more complex than two proteins. Scientists know, for example, that lipid metabolism goes awry, but identifying ...