Overall picks to win: 8-8 in Week 17 (173-82-1 for the season) Picks to win with 1-5 confidence: 4-7 (103-64-1) Picks to win with 6-10 confidence: 4-1 (70-18) Overall to cover the spread: 9-6-1 (130-117-9) Cover-the-spread picks with 1-5 confidence: 8-4-1 (107-93-8) Cover-the-spread picks with 6-10 confidence: 1-2 (23-23-1)

The Carolina Panthers ' Week 17 matchup against the Seattle Seahawks certainly looks tough on paper. Seattle enters at a strong 12-3 record and as the No. 1 seed in the NFC. But the Panthers have beaten the class of the conference twice before here in 2025, and they can certainly do it again.

The final weekend of the NFL regular season is upon us, and there are quite a few games that will determine postseason bids and seeding.

Sam Farmer makes his picks and predictions for the final week of the NFL regular season, with the 49ers beat the Seahawks and the Steelers prevailing.

The Jacksonville Jaguars will try to clinch the AFC South on Sunday when they host the division-rival Tennessee Titans in an NFL Week 18 matchup. The Jaguars (12-4) simply need a victory, but while the Titans are just 3-13,

Each pick has a confidence level of 1-10, with 10 being the most confident. For more information on the pick methodology, check out the Week 1 edition of this series. Keep in mind that since the idea here is to make high-percentage plays,

The Texans face Aaron Rodgers for the second time in as many seasons when they open the playoffs next week in Pittsburgh.

There's only one playoff spot up for grabs. Two new division champions were crowned in the early games Sunday. The Pittsburgh Steelers host the Baltimore Ravens at 8:20 p.m. Sunday with the AFC North on the line.