Molecular motors play critical roles in the formation of mitotic spindles, either through controlling the stability of individual microtubules, or by crosslinking and sliding microtubule arrays.

Microtubules are cell constituents that display several astounding properties and a unique pattern of behavior during the cell cycle. Microtubules are regulated by several proteins and complexes, and ...

Microtubule plus-end tracking proteins (+TIPs) play key roles in the regulation of microtubule dynamics in vivo. These proteins bind to and regulate microtubule “plus‐ends”, which are the dynamic ends ...

In a groundbreaking study published today in the prestigious Proceedings of the National Academy of Sciences (PNAS), researchers from Queen Mary University of London and the University of Dundee have ...

The motion of motor proteins on biopolymers is important for diverse biological processes. Actin, microtubules, and nucleic acids can serve as one-dimensional tracks on which motor proteins move.

A phase II randomized selection trial evaluating concurrent chemotherapy plus cetuximab or chemotherapy followed by cetuximab in patients with advanced non-small cell lung cancer (NSCLC): Final report ...

Atomic force microscopy (AFM) represents a better choice compared to light-based microscopy methods for the stufy of microtubules. For instance, the AFM can be used in buffers to image samples at a ...

An image of a large segment of a microtubule with a peeling tip. The colors highlight the different protofilaments that make up the tubule. The protofilaments are long biopolymers consisting of the ...