The locus coeruleus is a region of the brain that is instrumental in coordinating our mental processing and is the primary source of noradrenaline in the brain, which acts to regulate arousal states ...

A new study has linked signs of heightened arousal and reactivity -- a core symptom of posttraumatic stress disorder (PTSD) -- to overactivity of the locus coeruleus (LC), a brain region that mediates ...

A recent study has found that a tiny "turn-off-to-sleep" button in our brains that affects our sleep patterns, and its ...

Researchers at the University of Liège (BE) Institute are using ultra-high field 7 Tesla MRI to provide a better understanding of how sleep is regulated. We've known for a long time that sleep is good ...

Andrew Luskin conducted research on the brain's peri-locus coeruleus neurons while he was a UW Medicine neuroscience Ph.D. student. A small cluster of cells deep within our brains, called the locus ...

Tau aggregation begins not in the cortex, but in the brainstem. Does tangle deposition in the locus coeruleus, which often starts in a person’s 30s, presage Alzheimer’s disease? In the September 22 ...

Tsukuba, Japan—Mild exercise results in a feeling of mental clarity and enhances cognition and memory. A possible mechanism behind such effects is the activation of the arousal center in the brainstem ...

Optogenetic stimulation of the locus coeruleus noradrenergic neurons can increase wakefulness, and high-frequency stimulation decreases noradrenaline levels and produces loss of muscle tone similar to ...

Stress is implicated in diverse psychiatric disorders including substance abuse. The locus coeruleus–norepinephrine (LC–NE) system is a major stress response system that is also a point of ...

The locus coeruleus is emerging as a major new area of research interest, with many important functions such as regulating our attention and sleep. Anyone with insomnia knows the impatience and ...