In this webinar, Brian Haldeman will discuss how Leprechaun enables complete biophysical characterization of in-process or ...

Viruses are small obligate intracellular parasites with either a RNA or DNA genome that are surrounded by a protective protein coat and transfer their genetic material to infected cells. Lentivirus ...

Lentivirus is a genus in the family of Retroviridae that is very suitable for remodeling into gene transfer vectors due to its stable transgene expression, the ability to reach the nuclei of the ...

Figure 1: Stable gene silencing and production of processed shRNAs in a T-cell line by a lentiviral vector. Figure 2: Functional silencing of genes in cycling and non-cycling primary immune cells in ...

Lentiviral transduction is a popular delivery platform for applications such as CAR-T cell engineering or CRISPR-Cas9 gene editing, as it can transduce both dividing and non-dividing cells and ...

During the virtual Bioprocessing Summit in August, Cytiva reported that its new filtration process has advantages compared to traditional centrifuge approaches for removing viruses from suspension ...

Lentiviruses have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a huge advancement in technology and seemingly ...

This article explores the potential of lentivirus to address challenges in AAV-based gene therapy for hemophilia A.

In less than a year, Umoja Biopharma has made noise with its next-gen CAR-T immunotherapies, a few splashy hires and $263 million in financing. Now the Seattle-based startup is undergoing the next ...

GIBCO CTS LV-MAX Lentiviral Production System is a complete lentivirus production solution designed to produce high titer lentiviral vectors. This is the first optimized LV vector production system in ...

One vial of Lentivirus reagent (0.2 mL; >1x106 TU/mL) suitable for transducing cells with a non-perturbing nuclear restricted GFP label. Stable cell lines can be created under puromycin selection.