Vaccines are one of the most critical medical advancements in human history. This was recently demonstrated with the international coronavirus pandemic. The highly transmissible COVID-19 virus ...

The viral life cycle can be divided into two temporally distinct phases: infection and replication. Infection results in the introduction of the viral genome into the cell. This leads to an early ...

Vaccines based on replication-defective adenoviral vectors are being developed for infectious agents and tumor-associated antigens. Early work focused on vaccines derived from a common human serotype ...