From their first organic chemistry course, students learn that the more substituted an alkane, the weaker the remaining C-H bonds, and the more stable the molecule's corresponding radical. The reason ...

Saytzeff's rule is the result of empirical observations, and can be used to predict the outcome of elimination reactions. Now, ab initio calculations have provided the long-sought evidence to show ...

Figure 1: Anomeric effect in substituted tetrahydropyran. In this work, we studied molecules that exemplify the anomeric effect, including dimethoxymethane and substituted tetrahydropyrans, as well as ...