Researchers at Johns Hopkins University School of Medicine have created a single-nucleus RNA-sequencing resource to generate molecular signatures of cell types in five key regions of the human brain ...

Human beings, in all their complexity, are shaped by a myriad of thoughts, emotions, and experiences. Among the most profound aspects of our nature is our capacity for thought. This gift, however, can ...

The isolation caused by the coronavirus pandemic has been tough for most people, but it’s been particularly difficult for people with drug addictions. Last month, the National Center for Health ...

WORCESTER – It’s well documented that Worcester faces a homelessness and substance use crisis. Karen DiSaronno lives in a sober house. She was injured in a car accident during the pandemic and could ...

People who have a high sensation-seeking personality trait may be more likely to develop an addiction to cocaine, according to a Rutgers study. "Although many people try illicit drugs like cocaine or ...

But the conditions these rats were made to endure for the experiment — in effect, being alone in a cage with nothing but cocaine — is also a striking metaphor for the life circumstances known to be ...

An anti-cocaine vaccine has been used successfully on non-human primates, bringing it one step closer to approval for use in human addiction therapy. The vaccine (dAd5GNE) combines elements of the ...

Results of a new study suggest the prefrontal cortex-habenula circuit is potentially amenable for targeted interventions and prevention. White matter in the brain that was previously implicated in ...

These common examples underscore that addiction is not about responding to exposure to the same drug one took before; it has nothing to do with the same drug you took before. Then there's the fact ...

Weight loss medicines such as Ozempic and Wegovy, typically prescribed for obesity and type 2 diabetes, may have a surprising new application: treating drug and alcohol addiction. According to ...