A new study based on electron microscopy techniques at low temperatures demonstrates that, during mitosis, chromosome DNA is packed in stacked layers of chromatin. The research, published in EMBO ...

An analysis of chromosomes during mitotic cell division reveals that DNA and associated histone proteins condense through a process called phase transition, which helps them to resist the pushing ...

As the cell proceeds through the stages of cell division (from left to right: interphase, prometaphase, metaphase, and anaphase), chromosomes become progressively more compact through a combination of ...

The organization of DNA packaged in chromosomes during cell division has been very difficult to study experimentally. Researchers from the Universitat Autònoma de Barcelona have found that the ...

An international team of researchers co-led by Job Dekker, Ph.D., at UMass Chan Medical School, have identified rules that tell cells how to fold DNA into the tightly packed, iconic X-shaped ...

A mixture of DNA and proteins—known as "chromatin"—sits inside every cell nucleus as a jumbled puddle of genetic information. As cells prepare to divide during mitosis, the chromatin is condensed into ...

For the first time, scientists have directly observed events that lead to the formation of a chromosome abnormality that is often found in cancer cells. The abnormality, called a translocation, occurs ...

Robertsonian chromosomes are associated with infertility and Down syndrome, now cutting-edge DNA sequencing technology has unveiled the first comprehensive picture of their genetic rearrangements.

Scientists have finally uncovered the exact DNA sequence where human chromosomes fuse to form Robertsonian chromosomes, a mystery that has puzzled researchers for over a century. Using advanced genome ...