Proteins are digested into peptides for presentation by MHC to T cells. A recent paper in Science reports that some lipids also undergo processing in order to be presented by the unconventional class ...
Purified glycolipids containing galactose-α(1-4)galactose bind with Shiga toxin of Shigella dysenteriae 1 and Shiga-like toxins of Escherichia coli with high specificity in both thin-layer ...
Sensors that selectively detect glycolipids—molecules that are involved in infection, inflammation, and cancer progression—are hard to make. Most sensors target either the hydrophilic sugar head group ...
J. McLeod Griffiss, Herman Schneider, Robert E. Mandrell, Ryohei Yamasaki, Gary A. Jarvis, Janice J. Kim, Bradford W. Gibson, Randa Hamadeh and Michael A. Apicella ...
Current interest in glycolipid-based drugs started with work by a Japanese beer company. In the early 1990s, chemists at Kirin Brewery isolated a family of glycolipid natural products called ...
A xenogeneic PSMA DNA vaccine for patients (pts) with non-castrate metastatic (NCMPC) and castrate metastatic prostate cancer (CMPC)—A phase I trial of proof of principle No significant financial ...
Randomized phase II study of personalized peptide vaccination with cyclophosphamide pretreatment in refractory advanced biliary tract cancer patients. This is an ASCO Meeting Abstract from the 2014 ...
Glycoproteins are molecules that comprise protein and carbohydrate chains that are involved in many physiological functions including immunity. Many viruses have glycoproteins that help them enter ...
Leprosy has existed since at least Biblical times, yet scientists still don’t know exactly how Mycobacterium leprae causes the disease’s symptoms. Though antibiotics can treat the illness, researchers ...
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