The gut–islets axis connects nutrient sensing in the intestine with insulin secretion from the pancreas and plays an essential role in glucose regulation. GLP-1 released by intestinal L cells can ...

The study shows that fat tissue, when processed and cultured in a specific way, can self-organize into structures resembling ...

This is a preview. Log in through your library . Abstract Heterologous expression of proteins is used widely for the biosynthesis of biologics, many of which are secreted from cells. In addition, gene ...

Glycine, a non-essential amino acid derived from serine, plays an increasingly recognized role in metabolic regulation.

With antibiotic-resistant bacteria on the rise, scientists have been searching for ways to shut down the Type IV secretion system (T4SS), a protein complex on the outer envelope of bacterial cells ...

Now Niederweis and colleagues at the University of Alabama at Birmingham describe the mechanism of secretion and trafficking of that toxin, TNT, which is the major cytotoxicity factor for the pathogen ...

Gut microbes can regulate the exocrine and endocrine functions of the pancreas and hormone production of the gastrointestinal tract, findings that may help develop potential treatments for diabetes ...