This module explores the synthesis of amines with a focus on the reductive amination reaction. Numerous examples from the discovery and commercial manufacturing of pharmaceuticals are included. After ...

It’s a common enough scenario in many synthesis labs: you know what starting material you have, and you know what product you need but not quite what reaction conditions will get you there. Unless you ...

Researchers have developed an automated chemical synthesis machine that can take over many tedious aspects of chemical experimentation, freeing chemists to spend time on the more analytical and ...

Chemistry is all around us. From the widespread production of global food supplies to the metabolism that fuels the tiniest of microorganisms, everything in our surroundings is produced and controlled ...

The article provides a comprehensive review of the current progress and future prospects of high-pressure-driven chemical synthesis, offering constructive guidance for the design and development of ...

A single type of chemical structure that shows up again and again in modern medicine is the amide bond that links a carbonyl ...

Thought LeadersAndrew Kennedy & Jono WestVice President, Head of Scale-up & SafetySai Life Sciences In this interview, News-Medical talks to Andrew Kennedy and Jono West from Sai Life Sciences, about ...

Grinding stuff is probably one of the oldest ways to run a chemical reaction. For example, in the fourth century BCE, people extracted mercury from cinnabar by grinding the mineral with vinegar in ...

There’s an old saying about a dollar waiting on a dime. In other words, a monumental endeavor may become stuck at some point if a key preliminary element remains unavailable. The saying could be ...