Researchers have identified a single protein whose absence can cripple tumors in mice, slowing their growth and in some cases ...

Proteins are important molecules—but they aren’t the only molecules in a cell, and they don’t operate alone. In a new preprint, the team behind the protein structure prediction software RoseTTAFold ...

Life’s most indispensable molecules are not the serene, unchanging fixtures they might appear to be. Even the proteins that ...

Traditional analog ELISA readout systems need great volumes, which inevitably dilute reaction products, adding the requirement of millions of enzyme labels to develop signals that can be detected with ...

They build our bodies and orchestrate the molecular processes in cells that keep them healthy. They also present a wealth of targets for new medications. From everyday pain relievers to sophisticated ...

The proteins found in nature represent only a tiny fraction of the nearly limitless protein structures that could theoretically exist. By designing proteins de novo—from scratch—scientists can more ...

Despite their sophistication and power, traditional proteomics technologies have failed to provide comprehensive coverage. For example, with conventional mass spectrometry, a single experiment ...