A new artificial intelligence-powered tool can help researchers determine how well an enzyme fits with a desired target, helping them find the best enzyme and substrate combination for applications ...

Researchers have found a new enzyme, taken from Flavobacterium akiainvivens, that has a much broader specificity than the current leading alternatives. This analysis resulted in the identification of ...

Researchers have unveiled the crystal structures of UBA6 in complex with either ATP or the ubiquitin-like protein FAT10. These results provide the foundation to study the individual roles of UBA6 ...

Nitrilases are a unique class of enzymes that catalyse the hydrolysis of nitrile compounds to yield the corresponding carboxylic acids or amides. Their application in biotransformation processes has ...

In a new study published in Nature titled, “Custom CRISPR-Cas9 PAM variants via scalable engineering and machine learning,” researchers from Massachusetts General Hospital (MGH) and Harvard Medical ...

PNAS is the world's most-cited multidisciplinary scientific serial. It publishes high-impact research reports, commentaries, perspectives, reviews, colloquium papers, and actions of the Academy. In ...

Researchers studied double-strand breaks with complex damage and found that enzyme tools to resect the breaks are highly specific to the type of break to be repaired. Our cells are constantly dividing ...

Enzymes are biological catalysts that speed up chemical reactions in living organisms. They are essential for life, as they play a crucial role in various biological processes, such as digestion, ...

Researchers from the University of Massachusetts, Amherst, say they have made an important discovery on how cells handle stress. Using bacterial cells, the team found that a damage-repairing enzyme, ...