It is well known in physics and chemistry that equal charges repel each other, while opposite charges attract. It was long assumed that this principle also applies when enzymes – the biological ...

Emory University researchers led by Kyle Biegasiewicz have repurposed enzymes to produce diazo compounds from hydrazones under milder, greener conditions than traditional chemical methods (J. Am. Chem ...

A research team maps the key tasks that define modern enzyme engineering—function annotation, structure modeling, and property prediction—and explain how AI methods now accelerate each step, from ...

Reactions that can combine more than two molecular pieces in one go are a powerful way to build complexity quickly and save on costly isolation and purification. But the choreography for such a ...

A coenzyme is defined as an organic molecule that binds to the active sites of certain enzymes to assist in the catalysis of a reaction. More specifically, coenzymes can function as intermediate ...

Enzymes are proteins that facilitate biochemical reactions by acting as a catalyst, and thus, their expression and activity have a strong influence on the reactions taking place within cells. As ...

As a proof of concept, the engineers then used the same system to convert acetyl-CoA into malate, a commercially valuable chemical used in foods.