Despite extensive research on the molecular regulation of early tooth development, little is known about the cellular mechanisms driving morphogenesis prior to enamel knot formation. In a recent study ...

Figure 1: Deletion of Ctnna1 induces YAP nuclear localization as well as cell proliferation and inhibits EK formation. Figure 2: αE-catenin is required for maintaining proper cell polarity in the ...

Although several heat shock proteins have been investigated in relation to tooth development, no available information is available about the spatial and temporal expression pattern of heat shock ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, No. 23 (June 8, 2021), pp. 1-10 (10 pages) Development has often been viewed as a constraining force on ...

The single replacement from milk teeth to permanent teeth makes mammalian teeth different from teeth of most nonmammalian vertebrates and other epithelial organs such as hair and feathers, whose ...