Cytoplasmic dynein associates with dynactin to drive cargo movement on microtubules, but the structure of the dynein–dynactin complex is unknown. Using electron microscopy, we determined the ...

Nearly 50 years after the discovery of the walking molecular motor dynein, researchers have finally solved the first X-ray crystal structure of its massive motor domain. The milestone will permit ...

What is the dynein-dynactin complex and where is it found? What functions is this molecular motor thought to perform within cells? This is a macromolecular assembly is made up of two components, ...

A team led by scientists at The Scripps Research Institute (TSRI) has determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within ...

Our cells rely on microscopic highways and specialized protein vehicles to move everything—from positioning organelles to carting protein instructions to disposing of cellular garbage. These highways ...

Scientists have determined the basic structural organization of a molecular motor that hauls cargoes and performs other critical functions within cells. The complex's large size, myriad subunits and ...

Scientists have made important steps toward understanding how dynein--a "molecular motor"--walks along tube-like structures in the cell to move cellular cargo from the outer structures toward the cell ...

Researchers capture first-of-its-kind video of dynein–Lis1 protein interaction, supporting future drug development for neurological disorders. Our cells rely on microscopic highways and specialized ...

(Nanowerk News) An international team of scientists led by the University of Leeds has shed new light on the little-understood motor protein called dynein, thought to be involved in progressive ...