A large share of medicines developed today may never reach patients for a surprisingly simple reason: they cannot dissolve well enough in water. For most treatments, the oral route remains the gold ...
About 40% of marketed drugs are thought to be poorly water soluble. Development efforts might have to be redoubled, however, because between 70 and 90% of drug candidates in the pipeline are believed ...
These plots show powder X-ray diffraction measurements of three different types of formulations: simple mixing (a, d), the conventional evaporation/condensation ...
What is the process of oral drug absorption, and how has the Fa equation evolved? Oral drug absorption begins with administering a drug product, followed by a rapid disintegration process. The drug ...
Only about 4% of candidate drugs reach the market. The main culprits of this failure are due to issues with dosing , exposure and toxicity. Join us as Dr. Paul Leeson shares how improving candidate ...
A new study reveals the dual use of a FAP molecule that inhibits fibrosis and facilitates drug delivery, offering insights ...
Over 141,000 bottles of cholesterol medication have been recalled due to “failed dissolution specifications,” suggesting that the drugs did not pass a solubility test, or failed to dissolve at a ...
Aspire Biopharma’s new sublingual powder bypasses digestion, delivering alprazolam directly for faster anxiety and panic relief.