Potential autoimmune diseases therapies that target dendritic cells aim to either inhibit immunogenic dendritic cell functions or support their tolerogenic potential (Figure 2). Most strategies ...

Dendritic cells (DCs) serve as pivotal sentinels of the immune system, bridging innate and adaptive responses by processing and presenting antigens to T cells. Their inherent versatility enables them ...

Dendritic cells (DCs) are among the first immune sentinels to detect viruses, bacteria, or other challenges. These specialized messengers alert T cells while orchestrating either a measured calm or a ...

Why eczema is so common in infancy has remained a persistent mystery, with studies hampered by ethics concerns surrounding infant skin biopsies. A fragile skin barrier is the most commonly accepted ...

The immune system must be able to quickly attack invaders like viruses, while also ignoring harmless stimuli, or allergies can result. Immune cells are known to ignore or "tolerate" molecules found on ...

For decades, cancer immunotherapy has focused primarily on CD8+ cytotoxic T lymphocytes as the main executors of tumor cell ...

Treating the brain cancer glioblastoma (GBM) demands more than conventional strategies due to a mix of factors including the cancer’s genetic complexity, invasive growth, and immune resistance. A new ...

Why do diabetic wounds refuse to heal? A new scientific review highlights how disruptions in the timing and behavior of ...

The immune cell repertoire is composed of many different cell types that are orchestrated in response to infection and other pathogens that enter the body. As a result, the body can defend itself ...

Chronic diabetic ulcers represent one of the most challenging complications in modern healthcare, affecting over 131 million people worldwide and generating approximately $755 billion in annual ...