The human genome has to be carefully organized so it will fit inside of the nuclei of cells, while also remaining accessible to the cellular machinery that works to express the right genes at the ...

On February 28, 1953, two scientists, James Watson and Francis Crick, announced they had figured out the structure of DNA.

A fleeting DNA fold called i‑DNA can switch cancer‑related genes on and off, revealing a hidden structural weak point that ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

Alan Herbert, Founder and President of InsideOutBio, discusses the evolution of biological concepts related to DNA and ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a UCL-led research team. DNA is widely accepted to be formed of two strands that wind around one ...

DNA is the blueprint of life. Genes encode proteins and serve as the body's basic components. However, building a functioning ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.

Researchers developed e2MPRA, a high-throughput technique that simultaneously measures cis-regulatory element activity and epigenetic state. By analyzing thousands of sequences, the method showed that ...

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions, it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

Genetic circuit on a single DNA molecule as autonomous dissipative nanodevice. Credit: Nature Communications (2024). DOI: 10.1038/s41467-024-45186-2. In a new Nature Communications study, researchers ...