Figure 2: D4A inhibits 3βHSD, CYP17A1 and 5α-reductase enzymatic activity in the androgen pathway. Figure 3: D4A binds to AR, inhibits AR chromatin occupancy, expression of AR-responsive genes and ...
Researcher discovers metabolite of prostate cancer drug more effective at treating aggressive tumors
A metabolite of an FDA-approved drug for metastatic prostate cancer, abiraterone, has more anti-cancer properties than its precursor, researchers have discovered for the first time. Prostate cancer is ...
Metastatic prostate cancer generally responds initially to medical or surgical castration but eventually develops into castration-resistant prostate cancer (CRPC), which is driven by the metabolic ...
Look out Spotify, Deezer the music subscription service has launched an ad-supported streaming service in 150 countries today. Along with the ads, Deezer has also released Deezer4Artists (D4A), a new ...
Evaluating abiraterone responses in African Americans with metastatic CRPC. This is an ASCO Meeting Abstract from the 2016 Genitourinary Cancers Symposium. This abstract does not include a full text ...
Researcher discovers metabolite of prostate cancer drug more effective at treating aggressive tumors
Cleveland: Cleveland Clinic researchers have discovered for the first time that a metabolite of an FDA-approved drug for metastatic prostate cancer, abiraterone (Abi), has more anti-cancer properties ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results