The complete assembly of each human chromosome is essential for understanding human biology and evolution. Using complementary long-read sequencing technologies, we complete the first linear assembly ...

Research showed that a regulatory protein of chromosome structure (cohesin) is essential for proper maintenance of gene expression in the developing brain. Reduced cohesin impaired development of ...

In a leap forward for genetic and biomedical research, two scientists at the University of Missouri have developed a powerful new artificial intelligence tool that can predict the 3D shape of ...

Chromosomes are thread-like structures comprising DNA that are present inside the nucleus of every cell in the body. Specific segments of DNA are called genes. Every chromosome contains many genes, ...

HOUSTON - (Oct. 21, 2020) - How life works may come down to dumbbell-like bits of DNA. Rice University scientists on a long quest to study the structure and function of chromosomes have found that ...

Centromeres, specialized regions located at the center of chromosomes, are critical for ensuring proper cell division. During mitosis, centromeres serve as assembly sites for complex protein ...

We are entering into an exciting era of genomics where truly complete, high-quality assemblies of human chromosomes are available end-to-end, or from ‘telomere-to-telomere’ (T2T). Recently, the ...

In male cells of the fruit fly Drosophila, the X chromosome is twice as active as in female cells. Researchers have now discovered how the enzyme responsible recognizes the chromosome. In male cells ...

A picture of a mouse MII stage eggs with the location of chromosomes (green) and the distribution of the histone modification H3K4me3 (purple). The team confirmed that H3K4me3 was significantly ...