The brain is among the most “immune-privileged” of organs primarily through the highly selective permeability of the blood-brain-barrier (BBB), its minimal lymphatic drainage, the presence of ...

Major advance promises to accelerate the understanding and improved treatment of a wide range of brain disorders, including stroke, cerebral vascular disorders, brain cancer, Alzheimer's disease, ...

Physical exercise triggers extracellular vesicles (EVs)—tiny particles in the blood—to act as temporary transport shuttles for key hormone precursors.

The blood-brain barrier, a protective cell layer guarding the brain, blocks foreign bodies but also hinders drug delivery, complicating treatment of neurological disorders.Scientists have now devised ...

Focused ultrasound is just one strategy researchers are using to get drugs into the brain. This article first appeared in The Checkup, MIT Technology Review's weekly biotech newsletter. To receive it ...

While this protects the brain from external threats, it also presents a major challenge for treating neurological diseases, as many potentially therapeutic compounds are unable to cross. One potential ...

Experts are raising concerns about Benadryl’s ability to cross the blood-brain barrier and potential lasting impacts getty Benadryl has been used since the 1940s to stop allergy attacks and relieve ...

Medications like Ozempic mimic a naturally occurring hormone called glucagon-like peptide-1, or GLP-1, which helps regulate blood sugar and appetite. GLP-1 is primarily secreted from the intestines, ...

Focused ultrasound with microbubbles is a noninvasive procedure that transiently opens the blood-brain barrier (BBB) using low-intensity sound waves. The openings reseal within 24 hours. Using MRI to ...