Many diseases are the consequence of single or multifactorial gene defects. A greater understanding of the molecular, biochemical and genetic factors that entail the progression of a specific disease ...

Amplicon vectors 1 are HSV-1 particles identical to wild-type HSV-1 from the structural, immunological and host-range points of view, but which carry a concatemeric form of a DNA plasmid, named the ...

Viruses have evolved by borrowing and modifying cellular genes to become extremely efficient at nucleic acid delivery to different cell types, avoiding at the same time immunosurveillance by an ...