Extracytoplasmic function (ECF) sigma factors are a distinct subset of sigma factors that enable bacteria to respond robustly to a myriad of environmental challenges. By directing RNA polymerase to ...

Extracytoplasmic function (ECF) sigma factors constitute a large family of bacterial transcriptional regulators that direct transcription in response to various stresses and have different mechanisms ...

Transcription is the process of synthesizing messenger RNA by RNA polymerase based on the DNA sequence of a gene and is the initial step in gene expression. In bacteria, σ factor is a key component of ...

Streptomyces bacteria are our primary source of antibiotics, which are produced in the transition from vegetative growth to sporulation in a complex developmental life cycle. Previous research by ...