Scientists identify the protein DeltaFosB as the "master switch" that rewires the brain's memory and reward circuits, driving chronic cocaine addiction and relapse.

Cocaine addiction isn’t simply a failure of willpower — it’s the result of lasting biological changes in the brain.

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

I don’t drink anymore. I don’t smoke anymore.” He might have shrugged it off, but reports accumulated in his clinic and ...

A popular class of drugs for treating diabetes and obesity reduces addiction, including abuse of alcohol, tobacco, cannabis, ...

The impact of addiction on the brain is both catastrophic and comprehensive. When the brain is damaged by an addicting chemical, its executive functions—including judgment, decision making, and ...

It is frequently said that addiction occurs when drugs “hijack” the brain. It’s hard to nail down what that means, but it does rightly suggest that there is an involuntary takeover of the brain that ...

Researchers have used mouse models to study how cocaine addiction alters the brain, illuminating why relapse is common as ...

When a cocaine addict relapses, it isn't a matter of personal failure—it's the biological result of their brain's rewiring, ...

Prescription weight loss drugs have been lauded as the miracle drug for treating diabetes and obesity, but new research suggests that these drugs, known as glucagon-like peptide-1 (GLP-1) ...

GLP-1 medications may quiet the brain signals behind addiction, reducing substance use disorders and overdose risk across ...