The acid dissociation constant, K a, and its negative decadic log, pK a, are key life sciences parameters that describe molecular acidity. Specifically, these values indicate the protonation state of ...

This lab includes a theoretical explanation of how buffers work and how they are made, including a derivation of the Henderson-Hasselbalch equation. Students will use what they have learned to ...

The correlation of the first and second dissociation constants of symmetrical dicarboxylic acids with the distance apart of the ionizing groups is well known. An experimentally convenient correlation ...