Scientists have uncovered a powerful strategy that the brain uses to coordinate chemical signaling. In a new study, ...

Acetylcholine "conductors" in the striatum directly trigger serotonin release, offering new insights into the origins of OCD and chemical imbalances.

In 1921, Otto Loewi woke from a dream with the idea for an experiment that proved nerves communicate using chemicals, not just electricity. By showing that stimulating one frog’s heart released a ...

Acetylcholine regulates blood flow, but the source of blood acetylcholine has been unclear. Now, researchers at Karolinska Institutet have discovered that certain T cells in human blood can produce ...

More than 60% of complement inhibitor–naive patients with acetylcholine receptor–positive generalized myasthenia gravis (MG) in diverse clinical populations had a clinically meaningful reduction in MG ...

Acetylcholine (ACh) rechallenge may be a novel method to improve detection of coexisting coronary spasm endotypes, and at the same time, assess the treatment response to nitrate-based therapies, a new ...

Figure 2: Human alpha cells express vAChT and ChAT. Figure 3: Isolated human islets secrete acetylcholine (ACh) in response to alpha cell–specific stimuli. We further used the biosensor assay to ...

Karolinska Institutet researchers identified dopamine-acetylcholine disruptions in the basal ganglia as key contributors to autism-related behavioral inflexibility. Using advanced techniques like ...

The discovery of the first neurotransmitter — acetylcholine — was soon followed by the discovery of its hydrolysing enzyme, acetylcholinesterase. The role of acetylcholinesterase in terminating ...

Acetylcholine (ACh) is a neuromodulator with a central role in aversive learning - rapid conditioning to unpleasant smell, taste, or touch. These learning functions play out in cells called D2 ...