Philip Rivers and the Indianapolis Colts take on the San Francisco 49ers for Monday Night Football at Lucas Oil Stadium.

The Indianapolis Colts host the San Francisco 49ers on " Monday Night Football " in NFL Week 16 action. Both teams are watching injuries in the wake of Week 15 games.

San Francisco 49ers quarterback Brock Purdy joins NFL Network's "Inside Training Camp Live" to provide a state of the team's offense including chemistry with the wide receiver corps and better understanding head coach Kyle Shanahan's system entering year four.

The Indianapolis Colts have lost four of five games and their starting quarterback for the season. Where they stand in NFL power rankings.

ESPN’s Jeremy Fowler and Dan Graziano break down why the Colts may stick with Philip Rivers over Anthony Richardson.

The Indianapolis Colts competed, fought, and clawed to pull off the improbable against the Seattle Seahawks, but ultimately fell short, 18-16. After signing Philip Rivers to lead the squad, many believed this would be a disaster - I was essentially one of those people.

In the 26-0 victory over the Vikings in Week 13, the Seahawks offense recorded just 219 total yards. In the Week 14 win over the Falcons, Seattle was tied at the halftime break, 6-6. What kind of faith do we have in this Seahawks offense? At the very least, they are prone to slow starts.

The Indianapolis Colts visit the Seattle Seahawks in NFL Week 15 action: Live updates, score, highlights, Philip Rivers stats.