The clinical name for Down syndrome is trisomy 21, a condition in which a person is born with an extra chromosome, causing mild to moderate cognitive disability, developmental delays and physical challenges.

The Texas Rangers player, 28, will wear number 21 for the 2025 season in honor of his daughter Penelope, who was born with Down syndrome, according to the Major Baseball League. The genetic condition, known as Trisomy 21, results in an extra copy of chromosome 21.

Down Syndrome is also known as Trisomy 21, and Burger wants to raise awareness and contribute to research on the genetic condition.